Hematopoietic Stem Cells - 720 Words

Hematopoietic stem cells (HSCs) resides within the bone marrow, which serves as niche for the maintenance of HSCs. HSC niche maintain a balance between proliferation and differentiation not only during steady state of tissue homeostasis but also in stress conditions-like during bleeding, viral or bacterial infection or loss of blood cells caused due to toxins or chemotherapeutic agents. Identification of HSC niche has been a major challenge since years due to high mobility of HSCs. Unlike the other stem cell niche, where stem cells reside within their niche or in their proximity, HSCs keep travelling between different bone marrow compartments. Observing the complexity of HSC niche, Hanoun and Frenette said – â€Å"HSC niche is a maze; an amazing niche† (Hanoun and Frenette, 2013) Recently, diverse cell types have been identified that serve as niche for regulating HSCs. They include-osteoblasts, mesenchymal stem cells, non-myelinating Schwann cells, CXCL12 abundant reticular (CAR) cells, endothelial cells associated with leptin-receptor (LepR)-expressing mesenchymal stromal cells. Each of these cell types uses different signaling molecule for maintaining HSCs proliferation and differentiation (Lander et al., 2012). First cells to be recognized as HSC niche were-osteoblasts. Osteoblasts are bone- forming cells that line the bone-surface. HSCSs are present in close association with osteoblasts (Gong, 1978). First evidence indicating osteoblast as HSC niche came from the study ofShow MoreRelatedHematopoietic Stem Cells to Cure Leukemia980 Words   |  4 Pages Hematopoietic Stem Cells to Cure Leukemia Genetic Engineering consists in altering the DNA of a cell with the purpose of researching, as well as correcting genetic defects. (learn.genetics.edu) One of the human bodys cells has the ability to grow into any one of the bodys more than 200 cell types and this is called Stem Cells. They are not specialized and unlike mature cells, they can renew themselves and create new cells. Stem cells have a great potential, but extremely limited is theRead MoreHematopoietic Stem Cell Transplant Essay975 Words   |  4 PagesSince the first Hematopoietic stem cell transplant successfully carried out by Dr. Thomas in 1972, the technique has gained world- wide importance, and has become a potentially curative treatment for most neoplastic and non- malignant disorders  including Leukaemia, Sickle cell anaemia and Multiple Sclerosis (Alvarez Silva, 2017). However, complications such as graft-versus-host diseases (GVHD) and relapse of primary malignancy are substantial and are the leading causes of morbidity and mortalityRead MoreSymptoms And Treatment Of Cancer1530 Words   |  7 Pagescomprehension. Recognizing the scope of the problem is s ignificant. The overall incidence of GVHD is between thirty and sixty percent. GVHD has a fifty percent mortality rate. Risk factors for acute and chronic GVHD, treatment, outcomes after allogeneic hematopoietic cell transplant (HCT), relapse and disease-free survival after reduced intensity conditioning (RIC), and unrelated donors are all considered by the studies.1,3-6 So, the question to be considered: In cancer patients, is the survival rate and riskRead MoreThe Human Of Bone Marrow Transplantation1632 Words   |  7 Pagesand pathological traits that they share with other animals and humans. The field of BMT research has taken full advantage of these qualities, and mice have become one of the most commonly used BMT animal models. Transplantation (organ and hematopoietic) began in the early 20th century1. Several studies published between 1949-1953 139-141 documented that organs removed and immediately transplanted back into the same individual (autotransplants) were not rejected. However, organs from geneticallyRead MoreEssay on Bone Marrow Transplants1155 Words   |  5 Pagesyears, the emergence of bone marrow transplants as a therapeutic modality for fatal disease and as a curative option for individuals born with inherited disorders that carry limited life expectancy and poor quality of life (G). Over 4,500 hematopoietic stem cell [bone marrow] transplants performed on patients in the United States annually (H). Bone marrow transplants originally developed to allow the use of very high doses of cytotoxic drug treatments for malignancies, such as leukemia (B). Two typesRead MoreThe Use Of N95 Masks Versus Surgical Masks1500 Words   |  6 Pagesthe unit. This made me wonder why different institutions wo uld have different policies and what the actual best practice is according to evidence. The OHSU Policy #HC-NSG-BMT-205-POL Infection Control Policy for Adult and Pediatric Oncology/Hematopoietic Stem Cell Transplant (HSCT) Units states that patients shall wear an N-95 mask when outside the HEPA-filtered environment (OHSU, 2016). This is important to me from a leadership role development because as an informal nurse leader, it is my responsibilityRead MoreThe Role Of Haematopoietic Stem Cell Transplantation And Curing Disease2357 Words   |  10 Pageshaematopoietic stem cells in transplantation and curing disease 1. Hematopoietic stem cells Till and McCulloch described the two hallmarks of Haematopoietic stem cells to be long term self-renewal and the ability to differentiate into all various types of specialized blood cells, with one stem cell able to produce around a million mature blood cells after 20 divisions. The differentiation of these stem cells result in committed hemopoitic progenitor cells which give rise to cells from both the myeloidRead MoreAcademic Statement Of Purpose Of The University s Health Services Organization And Policy972 Words   |  4 Pagesa top medical school in China. In my junior years, through a series of research and clinical experience, I have become interested in the area of endocrine complications in long-term survivors after allogeneic stem cell transplantation. My thesis, titled â€Å"Effects of Hematopoietic Stem Cell Transplantation on Thyroid Function†, was completed at Ruijin Hospital. In the final year of my M.D. program, I was granted an opportunity to work as a resident in the Europe’s second largest bone marrow transplantRead MoreStem Cell Therapy Essay1036 Words   |  5 Pageskept increasing at accelerated pace. A lot of research areas had emerged for that purpose including one of the most fascinating and highly active areas at present, stem cells therapies. Due to self-renewal property and differentiation capability of stem cell, it becomes a new hope in modern treatment. The first successful case of stem cell therapy in human was reported in 1959. Bone marrow restorations were observed in leukemia patients who received total body irradiation subsequent by intravenousRead MoreDifferent Types Of Cell Research1597 Words   |  7 PagesFrom brain cells to skin cells, our body is made up of 200 different types of specialized cells. One of the most versatile types of cell is a stem cell. Stem cells are cells that have not been specialized yet; in other words, they do not have a specific job. For example, nerve cells work to send signals throughout your body, while stem cells do not have any specific functions. But they do possess the ability to develop into all of the other different types of specialized cells in our body. With regenerative

Disney Golden Age Of Animation - 2192 Words

1. Disney’ golden age of animation a) 1940 b)Though Disney films are considered wholesome and upbeat,characteristic of this era of films is their darkness. Though they are somewhat eerie and perhaps disturbing, scenes like these are typically sandwiched between two more upbeat and positive scenes, creating an extreme mood shift that engages all of the audience’s emotions. This style of animation also landed the â€Å"Golden Age† the nickname â€Å"The Tar and Sugar Era†, due to its dramatic jumps from dark to ‘sweet’. In just about every way these films pushed the limit of filmmaking. This era also includes the first and only time that breasts were openly shown in a Disney film, found in Fantasia. 2. Live action open a)Conductor as narrator b) Reminded of Early Childhood Centers where we encourage children to paint to the music...and having resulting conversations about their representations. Especially in this first piece! The animation did little to interpret the piece thematically. It was a visual interpretation of the structure of the music- gestural renderings of dynamics and tempo- With children, fast when the music goes fast, moving up and down†¦ 3.Toccata and Fugue in D Minor by Johan Sebastian Bach a)The Toccata and Fugue in D minor is a piece of organ music written,according to its oldest extant sources, by Johann Sebastian Bach. Its time of origin, narrowed down depending on author, lies between c.1704 and the 1750s.Show MoreRelatedAnalysis Of Walt s The Great Gatsby 1725 Words   |  7 PagesChicago, Illinois. Father, Elias Disney, and mother, Flora Call Disney, had a son that they named, Walter Elias Disney. He was one of five children, three boys; Herbert, Raymond, and Roy, and one girl, Ruth. After the birth of Walt, the family moved to Marceline, Missouri where they had a farm. Walt first got his inspirations of drawing through the environment around him. Being wrapped around animals and the nature aspects on a farm, it gave Walt at the early age of seven inspiration to create theseRead MoreWalter Walt Disney s Life898 Words   |  4 PagesWalter Elias Disney Walter Elias Disney was a film producer, cartoonist, screenwriter, and one of the first innovators for animation. He invented and was the founder Disneyland, an enormous theme park for family and friends of any age. These two theme parks are still popular and known throughout the entire world. He is known as a legend to the world. Walt Disney was born on December 5, 1901 in Hermosa, Illinois. His father was Elias Disney and his mother was Flora Call Disney. Walt Disney has threeRead MoreWalt Disney : A Pioneer Of Cartoon Films And As The Founder Of The Disney Company957 Words   |  4 Pagesimagination ¨ (Disney, 2014). Walter Elias  ¨Walt ¨ Disney is famous as a pioneer of cartoon films and as the founder of The Walt Disney Company. He was an American motion-picture producer, television producer, and a showman. Disney came from humble beginnings but ended up transforming the entertainment industry. Walt Disney had a challenging childhood, grew up and chose a career that would liven up his life, achieved many accomplishments, and left a legacy for years to come. Childhood Walt Disney was bornRead MoreAnimation : The Millennium Age Of Animation793 Words   |  4 PagesThe History of Animation Animation has been around since the beginning of times. Animation is not just something of the cinema, which animation dominates today. Animation is creating and capturing an illusion of what looks like an object moving when shown in order. So how long has animation really been around? It has been around since the beginning of mankind and continues to thrive in today’s era of animation, The Millennium Age of Animation. People have been depicted animation since mankind cameRead MoreWalt Disney s Early Life816 Words   |  4 PagesThe beginning- Walt Disney’s early years- Walt Disney was born in Chicago, IL on December 5, 1901. His family soon moved to a Missouri farm where then he began to draw. That farm failed so they moved to Kansas City where Walt started delivering newspapers. In 1917, the family moved to Chicago. Walt started making art for his high school! Walt took classes at the Art Institute of Chicago, and tried to get into the U.S. Army. He got rejected for being underage so he joined the American Ambulance CorpsRead MoreSteamboat Music, Silly Symphonies, and Fantasias of Sound1200 Words   |  5 Pagescurious, and curiosity keeps leading us down new paths.† -Walt Disney With one man and a mouse, the history of the film, animation, and soundtrack world was changed forever. Co-founder of Walt Disney Productions, now known as The Walt Disney Company, Walt Disney changed the game of the movie industry with his animated films, ushering in a new era of feature animations. Not only were his animations original, but they were innovative. Disney constantly pushed himself to find new ways to advance the mediumRead MorePixar Animation Changed The World1537 Words   |  7 Pages Pixar Animation changed the game of animation, but how? Is it the beautiful quality, the picturesque feel, or the new change that brought the animation industry to a new focus? Animation is so much more than what we think or know about it. It is an art that challenges the way we look at the world. It brings a new level of realism and imagination to our bleak, everyday lives. Animation changed not only from Disney but also from the 3D beauty that lead the world to an unders tanding of whatRead MorePixar1258 Words   |  6 PagesOVERVIEW Introduction Pixar Animation Studios is an Academy Award  ®-winning computer animation studio with the technical, creative and production capabilities to create a new generation of animated feature films, merchandise and other related products. Pixar s objective is to combine proprietary technology and world-class creative talent to develop computer-animated feature films with memorable characters and heartwarming stories that appeal to audiences of all ages. Feature Films On NovemberRead MoreAnalysis Of Walt Disney s The Great Gatsby 1660 Words   |  7 Pagesset the building blocks for animation. This is the man who created the happiest place on earth. This.Is. Walt. Disney *que cartoon* Walt Disney’s Steamboat Willie, the first of many other Mickey Mouse cartoons, was a great hit all over the world. But it took a difficult and long journey to be where his legacy is today. Lets look back to where it all began†¦. Walter Elias Disney was born on December 5, 1901 in Chicago, Illinois. His parents were Elias and Flora Disney. He was born into the familyRead MoreAnalysis Of Animal Subjects Of The Graphic Novel 1158 Words   |  5 Pagesportrayed and how their stories pan out. As society changes, so did the animals in animation.: â€Å"as the twentieth century progressed, the definition of animal hero in realistic animal fiction generally changed from wild animals that were heroic for surviving against all odds to domesticated animals that were heroic for rescuing humans from wild beasts† (Oswald 135). This is clear even within one studio. Take the Disney films Bambi and Bolt. Bambi is a 1942 classic movie, featuring a small deer becoming

Anti Violence Essay Free Essays

Anti violence essay Seven years ago I did not think violence existed in America. The most violent act ever committed was the tragedy of the World Trade Center in 9/11/01. The Trade Centers had been the target for something so horrible, and I thought at the time, ‘This will change the world. We will write a custom essay sample on Anti Violence Essay or any similar topic only for you Order Now † I was right about that fact: our airports are more secure, we have to have pass-ports anywhere you go now, you have more thorough bagage checks, and they’re more selective as to what’s in your purse before boarding a plane. I think the most secure place in America right now is our power plants. They have increased security at all our power plants, including the nuclear plants, and also there is air space around each plant so planes have to keep their distance from them. Homeland Security is a common word in our homes today because of 9/11. I wanted to know how. Wanted to know why. Wanted to know what our leaders reactions would be. The world trade center killed many people that my friends knew and loved; that can never be replaced. This act changed the way my friends lived, loved, and acted in school. This spine-chilling nightmare was committed because terrorists took over three planes that flew into the giant buildings. The causes of this violence is the hatred between countries, states, or nations. The hatred is then passed down to the youth generation, because we hear, and see the dislike between the grown-ups. Children learn from the wisdom and actions of what the elders do. Shooting, stabbing, verbal abuse, physical abuse, and gang fights are a few examples of youth violence. All of these exist in schools, neighborhoods, malls, the movies and even in your own home on the internet. Schools have tried to stop it but there is still a lot of verbal abuse anywhere in the school system you go. Youth violence can be stopped by reporting abuse, shooting, stabbings, and anything to do with gangs. It can also be solved by not being the one that does bulling or any of the things listed above. I think it is funny how teachers wonder about why no one reports violence in America. My say on the matter is the kids are scared it will only get worse if we tell a teacher or principal or any adult because they use our name and our grade to the bully or person that Bothers you. How to cite Anti Violence Essay, Essay examples

Corporate Social Responsibility In Event Management- Free Sample

Question: Using a sport or event company of your choosing, you are required to critically analyse the three arguments, using examples to illustrate your point(s). Use the information to determine which argument for CSR is most important to your company. Assessment Criteria Analysis of the three arguments with regard to your company Selection and justification of the most important argument Evidence of background reading Quality of referencing Answer: Introduction: The concept of corporate social responsibility has varied dimensions and perspectives, particularly moral, rational and economic. On one hand management responsibilities are focused towards respective stakeholders, while others argue regarding social goals, and yet others prioritize more on legal compliance rather than social aspects. This report aims at highlighting and analyzing all the three arguments for an organization named Wonderland Events Ltd. to engage in the activities related to Corporate Social Responsibility particularly moral, economic and rational. The report encompasses the critical analysis of all the arguments incorporated within the mentioned organization. Three dimensions: Moral, rational economic The organizational commitment may significantly derive from economic self-interest or ethical concern involving moral sustainability. When the event managing company adds value it is considered to be positive as well as significant (Nalband and Kelabi, 2014). It is believed by all major organizations such as Wonderland Events Ltd. that taking great care of people as well as community are directly related to long-term business survival. The main attributes which define essential characters of the organization as well as contemporary turn towards values show evolution stated as corporate personality. Corporate identity exhibits the actual functionalities of the organization. The organization has been steadily maintaining its key responsibility to make profit. However, it is said to incorporate quite successfully the corporate social responsibility towards all stakeholders (Mishra, n.d.). To highlight on the social aspect foremost, the organization is concerned about the relationship amidst its business and that of the society. In this respect, Wonderland Events Ltd incorporates principles of corporate social responsibility to benefit not only itself but the society as a whole. This involves sourcing fair and quality performances and services, such as agreeing to pay fairly to the employees and suppliers. It also involves taking upon endeavours which benefit society, such as using own resources in organizing charitable fundraisers (Mazereeuw-van der Duijn Schouten, Graafland and Kaptein, 2013). With reference to the social responsibility of the organization towards its community at large, the employers of Wonderland Events Ltd aim at maintaining a proper balance amidst its business requirements and that of the entire society where it operates and survive. It follows the principle that business must be so managed as to make public good to become good for the organizati on. The firm practices in a way that it reflects in its various policies that are associated with environmental protection, conservation of natural resources, pollution control, rural development, establishing operational units at the backward regions, giving employment opportunities to all socially challenges individuals or weaker sections of the society, and also providing relief when required to the people suffering in natural calamities (Ratajczak, 2014). Competition within business environment is very common but enhancing the bottom line within social terms needs that the organization fosters the environment where it may succeed. Efforts from the whole society would allow the firm to continue with its existence, and this would foster goodwill amidst the organization as well as the society (Marens, 2014). With respect to economic aspect, it refers to the impacts that the corporate social responsibility of Wonderland Events Ltd has upon the finances of the organization. Since the concept of CSR does not cost any amount, there is no cause for its limitations in organizations. The event management company makes it a point to meet economic responsibilities in context to reasonable returns towards its investors, fair prices towards customers, fair compensation system towards employees, etc. Hence, accomplishment of economic responsibilities acts as the foremost responsibility of the firm. This is essential for the firm to survive in the business environment (Liu et al., 2013). Research exhibits that economic sustainability principle of Wonderland Events Ltd focuses on the long term accomplishments since this is the foremost requisite of an effective firm. Corporate identity exhibits the actual functionalities of the organization. The organization has been steadily maintaining its key respo nsibility to make profit. However, it is said to incorporate quite successfully the corporate social responsibility towards all stakeholders. Studies reflect that this event management firm is highly committed towards equal opportunities for both employees and its clients. It believes that by practicing equal opportunities enhances an efficient performance in the service it is engaged in. To highlight rationally, the firm ensures that none of its employees receive unequal treatments on the basis of discriminatory aspects such as gender, race, marital status, colour, age, sexual orientation, disability or even religious beliefs (Kim et al., 2014). The organization is identified to be one that ensures that required resources are to be made available for ensuring that it conducts its responsibilities in the most effective and desired manner. It makes a practice of reviewing all policies to ensure that these are most relevant to the business. The organization is committed to creating a safe work environment internally and externally. The only aspect that is concerning for this firm is related to generating of appropriate infor mation, supervision or training when required following health-related regulations (Jacqueminet, 2013). The health and safety policy of the firm upholds a favourable work environment towards all its employees, clients and stakeholders. However it only requires develop, incorporate and review on a continuous basis its policies related to health and safety. On a rational term, the firm is said to operate clearly, fairly in all other aspects so as to ensure that employees perform at a high standard (Wali and Boujelbene, 2010). It gives efforts in maintaining equitable benefits as well as providing reward systems for increasing performances in the organization. Wonderland Events Ltd ensures that its clients are well aware of carbon offsetting as well as giving them the choice to make planning of events with the lowest adverse impact upon environment (Hasnaoui and Freeman, 2010). The firm is sad to encourage honest conversations to promote good working bonds in terms of current corporate accountability policies as well as legislation. It emphasizes its stakeholders and maintains rational business relations. These stakeholders are quire affected by the functions of the firm. These involve employees, public members, and suppliers. For instance, it is able to increase its output by making its employees work more, but on the other hand it also considers the impact it would have on the members and not just its objectives. Conclusion: It may be assessed from the study that the firm incorporates all the three arguments quite suitably within its environment. It is also identified that Wonderland Events Ltd is more concerned with its social image. This is because events management is all about being social and maintaining social reputation and recognition in order to be success. Here it is seen that this organization prioritizes being socially effective as it understands well that in the present business environment it is essential to be socially responsible for the entire society. It also involves taking upon endeavours which benefit society, such as using own resources in organizing charitable fundraisers. With reference to the social responsibility of the organization towards its community at large, the employers of Wonderland Events Ltd aim at maintaining a proper balance amidst its business requirements and that of the entire society where it operates and survive. References Hasnaoui, A. and Freeman, I. (2010). Diffusion and Implementation of Corporate Social Responsibility (CSR) : The Role of Information and Communication Technologies (ICT).Management Avenir, 39(9), p.386. Jacqueminet, A. (2013). Managing Levels of CSR Implementation in an MNC: The Role of Receptivity to Institutional Pressures.Academy of Management Proceedings, 2013(1), pp.15600-15600. Kim, K., Kim, M., Qian, C. and Park, B. (2014). Effects of CSR on Firm Financial Performance: A Competitive-Action Perspective.Academy of Management Proceedings, 2014(1), pp.13277-13277. Liu, J., Tian, Z., Cheng, P. and Yang, W. (2013). Value Chain Extension: Making Sense of Strategic CSR Implementation.Academy of Management Proceedings, 2013(1), pp.13757-13757. Marens, R. (2014). The Price of Autonomy: The Chandlerian Firm and the Changing Face of Explicit CSR.Academy of Management Proceedings, 2014(1), pp.10711-10711. Mazereeuw-van der Duijn Schouten, C., Graafland, J. and Kaptein, M. (2013). Religiosity, CSR Attitudes, and CSR Behavior: An Empirical Study of Executives Religiosity and CSR.Journal of Business Ethics, 123(3), pp.437-459. Mishra, D. (n.d.). Post-Innovation CSR Performance and Firm Value.SSRN Journal. Nalband, N. and Kelabi, S. (2014). Redesigning Carrolls CSR Pyramid Model.JOAMS, pp.236-239. Ratajczak, M. (2014). The implementation of selected elements of the CSR concept on the example of agribusiness enterprises from Warmia and Mazury.Management, 18(1). Wali, S. and Boujelbene, Y. (2010). The effect of TQM implementation on firm performance in the Tunisian context.IJPQM, 5(1), p.60.